This game is seemingly as cursed as the vampires in it. From the recent video it seems they're streamlining the RPG elements, making it more like a Mass Effect than a Dragon Age (the protagonist is voiced, likely cutting many dialogue options).
I do think some of the changes could be interesting, like being an Elder instead of a Fledgling. Although I think many decisions are made to be the opposite of the original, even the setting reflect this: instead of LA in the summer it is set in Seattle in winter.
I honestly don't think I will buy it on release. Probably pirate it when all DLC is out along with the fixes.